Receptor
|
Major Functions
|
|
Sympathetic
|
α
1
|
↑
vascular smooth muscle contraction, ↑ pupillary dilator muscle contraction
(mydriasis)
|
α
2
|
↓
sympathetic outflow, ↓ insulin release
|
|
β
1
|
↑
heart rate, ↑ contractibility, ↑ renin release, ↑ lipolysis
|
|
β
2
|
Vasodilatation,
bronchodilatation, ↑ heart rate, ↑ contractibility,
↑
lipolysis, ↑ glucagon release, ↓ uterine tone
|
|
Para-sympathetic
|
M
1
M
2
M
3
|
CNS,
enteric nervous system
↓
heart rate and contractibility of atria
↑
exocrine gland secretions, ↑ gut peristalsis, ↑ bladder contraction,
bronchoconstriction, ↑ pupillary sphincter muscle contraction (miosis),
ciliary muscle contraction (accommodation)
|
Dopamine
|
D
1
|
Relaxes
renal vascular smooth muscle
|
D
2
|
Modulates
transmitter release, especially in brain
|
|
Histamine
|
H1
|
↑
nasal and bronchial mucus production, contraction of bronchioles, pruritus
and pain
|
H
2
|
↑
gastric acid secretion
|
|
Vasopressin
|
V
1
|
↑
vascular smooth muscle contraction
|
V
2
|
↑
H2O permeability and reabsorption in the collecting tubules of the kidney
|
Friday, September 19, 2014
RECEPTORS-NERVOUS SYSTEM-ACCION
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